CTAG CTAG DNA from a healthy person DNA from a person with CF III| |||I

Q: What type of mutation occurred to produce the abnormal sequence (nonsense or missense)? Explain your…

A: A mutation is a change in a DNA sequence.

Q: The period gene of Drosophila melanogaster encodes for a stretch of Thr-Gly repeated in tandem. In…

A: In this question, it is given that the allele with 20 Thr-Gly repeats produces an amplicon of size…

Q: Which type of mutation best describes a change in a non-coding region of the genome?

A: Mutation: Normal DNA contains a particular sequence of DNA. If the sequence of DNA is changed due to…

Q: Illustrate and give the normal sequence and the mutated sequence in Leigh's syndrome

A: A disease is a state of unhealthiness of the physical body, mind and social interaction. A disease…

Q: a. Which gene is mutated in individuals with sickle-cell anemia? b. What are the major symptoms of…

A: Hi! Thanks for your question. As you have posted multiple questions and have not mentioned which one…

Q: Cystic Fibrosis is caused by a mutation in the CFTR gene, and an ideal form of treatment would be to…

A: Cystic fibrosis is an inherited life threatening disorder that causes severe damages to lungs,…

Q: Define the silent mutation in DNA? (2.5 marks) 2) What is the codon usage bias? (2.5 marks) 3)…

A: Answer 1)  Silent mutations are DNA mutations that do not result in a change to the amino acid…

Q: How can we estimate the age of a mutation?

A: Mutation is defined as sudden inheritable change that occurs in the DNA sequence. Mutation occurs…

Q: The following is a list of mutational changes. For eachof the specific mutations described, indicate…

A: Hello there! As you have posted multiple questions, we are answering only the first three questions…

Q: Silent mutations that occur in DNA are quite common in living cells and usually involve no effects…

A: A mutation is a change that occurs in our DNA sequence, which might occur due to mistakes when the…

Q: Based on the following wild type DNA sequence, indicate if each of the mutations should be…

A: The central dogma is DNA --> mRNA --> Protein. Hence, any mutations in the DNA lead to changes…

Q: Briefly explain the frameshift mutation ?

A: Mutation can be defined as the change that occurs in the DNA sequence which is caused by mistake or…

Q: It is possible to take the DNA of a gene from any source and place it on a chromosome in the nucleus…

A: Recombinant DNA technology is the process in which the recombination of genetic material takes place…

Q: How might a single base pair difference about 100 bases before the start codon of the CFTR gene…

A: Cystic fibrosis (CF) is a genetic disease that occurs due to mutated gene in chromosome 7 in human…

Q: Mention four human genetic diseases that result from single gene mutation, please answer this…

A: Because of their uncomplicated inheritance patterns (recessive or dominant) and relatively simple…

Q: The letters ABCDEFGH represent a normal DNA sequence. Indicate the type of mutation present in each…

A: Whenever there is a normal DNA sequence, but after DNA replication, or due to cellular stress or due…

Q: It has been noted that most transposons in humans and other organisms are located in noncoding…

A: Transposons: Transposons are also referred to as "jumping genes" in which they have the ability to…

Q: If the mutation causing Tay Sachs disease involves a C to T change at position 4 in the sequence…

A: Gene probes are of three types: gene-specific probes, polymorphic probes and oligonucleotide probes.…

Q: Which of the following types of physical mutagens produces thymine dimmer mutations? A- gamma rays…

A: Given:       Physical mutagens produces thymine dimmer mutations.

Q: Would a gain of function mutaion that occurs in the first exon of a gene with twelve exons more…

A: Gain-of-function type of mutation is a mutation in which the altered gene product possesses a new…

Q: How many different explanations can you think of for the observation that the rate of mutation…

A: A mutation is a change in our DNA sequence that happens as a result of errors in DNA copying or…

Q: Next-generation sequencing reveals that six new mutations have occurred in the coding regions of…

A: Mutations are sudden heritable changes in the genetic make up of an organism because of several…

Q: please solve the  following: (a)Explain how a mutation effects a genotype. (b) Explain how a…

A: The genotype refers to the hereditary material passed among generation, and the phenotype is…

Q: Upon going through the complete process of gene expression, which amino acid would be most likely to…

A:

Q: What type of mutation is shown in the diagram?   Why do you think this type of mutation is referred…

A: Mutations are alterations in the gene sequence due to presence or interference of certain mutagenic…

Q: Which of the following statements about a transversion mutation in the sequence AGC is true?

A: Transversion alludes to a point mutation in DNA in which a solitary (two rings) purine is changed…

Q: Which of the following mutagens can substitute bases in DNA because of structural similarity?…

A: A mutagen is defined as any physical or chemical substance that can cause a mutation by altering an…

Q: Two types of mutations discussed in this chapter are 1) nucleotide changes and 2) unstable genome…

A: Mutations are sudden heritable changes in the DNA sequence of a gene and are responsible for all the…

Q: As we described in class, in the early 1960's Francis Crick and colleagues set out to determine how…

A: Introduction  Genetic code   The sequence of bases that encodes a functional protein molecule is…

Q: In studies of frameshift mutations, Crick, Barnett, Brenner, andWatts–Tobin found that either three…

A: The mRNA (messenger ribonucleic acid) contains an ORF (open reading frame) which is a continuous…

Q: What is the resulting polypeptide: _______________________________________________________? What…

A: Central dogma is the central processing part in which DNA is converted into m RNA by transcription…

Q: In a genomic analysis looking for a specific disease gene,one candidate gene was found to have a…

A: The discovery, measurement, or comparison of genomic properties such as DNA sequence, structural…

Q: 1) Define the silent mutation in DNA?  2) What is the codon usage bias?

A: Hi! Thanks for the questions. As you have posted multiple questions, I will be answering the first…

Q: TACAT

A: Solution :There are three types of DNA Mutations: base substitutions, deletions and insertions.

Q: Which of the given disorder can be seen in an individual when the mutation includes substitution of…

A: Purines and pyrimidines are nitrogenous bases present in nucleic acids. Substitution of purine by…

Q: Basic features of the central dogma of molecular genetics is

A: DNA is a molecule made up of two polynucleotide chains that form a double helix and carry genetic…

Q: What is the Central Dogma of Molecular Genetics? What impact did the discovery of RNA tumor viruses…

A: The Central Dogma was first proposed in 1958 by Francis Crick. He was also the discoverer of the…

Q: How do germ-line mutations differ from somatic mutations? Germ-line mutations are reversible, while…

A: Mutations are the random changes in the genome of organisms.

Q: Two types of mutations discussed in this chapter are 1) nucleotide changes and 2) unstable genome…

A: The mutation is a change that is due to a change in DNA due to some environmental factors or damage…

Q: sequences below to determine what type of mutation has occurred by comparing the normal sequence to…

A: Original sequences produce normal or regular phenotypes. Mutated sequences produce new phenotypes.…

Q: Provide one example of a clinical implication of a “silent mutation” that proven to have an effect…

A: Answer: SILENT MUTATIONS  are the mutations in the DNA that do not have an observable effect on the…

Q: What is the minimal number of insertions/deletions of nucleotides that would result in a frameshift…

A: A mutation happens when a DNA (deoxyribonucleic acid) gene is broken or modified causing the change…

Q: What are the chances of occurrence of hypomorphic mutation?

A: Mutation is defined as the sudden inheritable change that occurs in the DNA sequence.  It is caused…

Q: A mutant strain of bacteria is isolated in which the amino acid glutamine is often erroneously…

A: Answer of the question given below...

Q: Is each of the following mutations a silent, missense, nonsense, orframeshift mutation? The original…

A: The mutation is a sudden, stable, and heritable change in the organism’s genome. It can occur due to…

Q: 5'-ATGTCCACTGCGGTCCTGGAAAACCCAGGC-3’ wild-type allele 3'-TACAGGTGACGCCAGGACCTTTTGGGTCCG-5’…

A: The term mutation refers to the alternations in DNA sequences. The chemicals or other substances…

Q: Cystic fibrosis can arise from a rare, short, in-frame deletion within the CFTR gene, which creates…

A: Cystic fibrosis (CF) is a disease that inherits and affects the lungs, digestive system, and other…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.