Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN: 9781285866932
Author: Lauralee Sherwood
Publisher: Cengage Learning
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Textbook Question
Chapter 3, Problem 7UC
Describe the contribution of each of the following to establishing and maintaining membrane potential: (a) the
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A) When the voltage gated K+ channels open K+ moves down its concentration
gradient from the ECF to inside the cell.
O B) The value for resting membrane potential is closer to the EK+ (Equilibrium
potential for K+) than the ENa+
O C) When the membrane potential is at rest the membrane is more permeable to
Na+ than it is to K+
O D) Closing of the voltage-gated Na+ channels increases the permeability of the
membrane to Na+
How can the resting membrane potential of a membrane be calculated using the Goldman-Hodgkin-Katz (GHK) equation?
The resting membrane potential…A) Can be approximated using the Goldman-Hodgkin-Katz equation.B) Represents a difference in charges across the cell membrane, resulting mostly from the passive flow of Na+ions.C) Has no influence on the driving force that acts on different ions across the cell membrane.D) Is equally dependent on the concentration gradients of potassium and sodium across the cell membrane.E) Becomes hyperpolarized during an excitatory graded potential.
Chapter 3 Solutions
Human Physiology: From Cells to Systems (MindTap Course List)
Ch. 3.1 - Draw how phospholipid molecules align themselves...Ch. 3.1 - Prob. 2CYUCh. 3.1 - Prob. 3CYUCh. 3.2 - Prob. 1CYUCh. 3.2 - Prob. 2CYUCh. 3.2 - Prob. 3CYUCh. 3.3 - Prob. 1CYUCh. 3.3 - Distinguish between passive and active forces that...Ch. 3.4 - List the means of unassisted membrane transport.Ch. 3.4 - Prob. 2CYU
Ch. 3.4 - Prob. 3CYUCh. 3.5 - Draw a graph comparing simple diffusion down a...Ch. 3.5 - Describe what causes the carrier to change shape...Ch. 3.5 - Distinguish between symport and antiport.Ch. 3.6 - Prob. 1CYUCh. 3.6 - Describe the relative contributions of k+ and Na+...Ch. 3.6 - Prob. 3CYUCh. 3 - The nonpolar tails of the phospholipid molecules...Ch. 3 - Prob. 2RECh. 3 - Prob. 3RECh. 3 - At resting membrane potential, there is a slight...Ch. 3 - Using the answer code on the right, indicate which...Ch. 3 - Prob. 6RECh. 3 - Prob. 7RECh. 3 - Prob. 1UCCh. 3 - Prob. 2UCCh. 3 - What two properties of a particle influence...Ch. 3 - Prob. 4UCCh. 3 - Prob. 5UCCh. 3 - Prob. 6UCCh. 3 - Describe the contribution of each of the following...Ch. 3 - Using the Nernst equation, calculate the...Ch. 3 - One of the important uses of the Nernst equation...Ch. 3 - Using the Goldman-Hodgkin-Katz equation, determine...Ch. 3 - When William H. was helping victims after a...Ch. 3 - Which of the following methods of transport is...Ch. 3 - Assume that a membrane permeable to Na+ but not to...Ch. 3 - A solution may have the same osmolarity as normal...Ch. 3 - Prob. 4TAHLCh. 3 - Prob. 5TAHL
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- Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forwardThe resting membrane potential…A) Can be approximated using the Nernst equation.B) Is established by a difference in charges across the cell membrane, with the inside more positive than the outside.C) Has no influence on the driving force for flow of a particular ion across the cell membrane.D) Is more dependent on the passive flow of potassium vs. sodium ions through leak channels across the cell membrane.E) Stays the same during an action potential.arrow_forwardAssume that in a neuron, the plasma membrane permeability values for potassium (K+), sodium (Na+), and Cl− are the following: PK = 1, PNa = 12, and PCl = 0.5. Based on physiological concentrations of K+, Na+, and Cl− (refer to the table), determine the membrane potential in this neuron.arrow_forward
- The differences in relative concentrations of ions inside and outside the cell act as an electrical force. The specific ion(s) MOST important to establishing the resting potential in neurons would be Multiple Choice a) Na+. b) K+. c) intracellular anions (e.g., proteins). d) H+. e) Na+, K+, and intracellular anions are all important.arrow_forwardMatch each type of membrane potential (resting, threshold, graded, or action) to its definition: a) The membrane potential at which voltage gated sodium channels open. b) The membrane potential that triggers the action potential. c) Change in membrane potential that may or may not reach threshold and that may be depolarizing or hyperpolarizing. d) Rapid, strong depolarization followed by immediate repolarization. This potential is self-renewing if the right ion channels are nearby.arrow_forwardWhat role do the Na+/K+ pumps play in establishing the resting membrane potential?arrow_forward
- Describe the contribution of each of the following to the establishment and maintenance of membrane potential: Part A Na+K+ Pump Passive movement of K+ across the membrane Passive movement of Na+ across the membrane Part B Resting membrane potential is approximately -70mV. Explain what resting membrane potential is and what -70mV refers to.arrow_forwardWhat effect does an increase or a decrease in extracellularK+ concentration have on resting membrane potential?arrow_forwardCalculate the equilibrium membrane potentials to be expected across a membrane at 37 °C, with a NaCl concentration of 0.10 M on the “right side” and 0.01 M on the “left side”, given the following conditions. In each case, state which side is (+) and which is (-). (a) Membrane permeable only to Na+ (b) Membrane permeable only to Cl– (c) Membrane equally permeable to both ionsarrow_forward
- What is the resting membrane potential? What three factors create the resting membrane potential?arrow_forwardWhat condition is required for a specific ion to contribute to resting membrane potential?arrow_forwardIf a cell with the following ion concentrations had a resting membrane potential of -40mV which of the following can you conclude? Extracellular: Cl- = 110 mM, Na+ = 145 mM, K+ = 5mM. Intracellular Cl- = 20 mM, Na+ = 10 mM, K+ = 140mM a) At rest it is only permeable to potassium b) At rest it has some permeability to more than one of these ions c) At rest it is only permeable to chloride d) Rest it is not permeable to sodiumarrow_forward
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