Which of the following best describes statins mechanism of action? Group of answer choices It is an irreversible inhibitor It binds to the allosteric site of HMG-CoA reductase It directs the rate-limiting step in cholesterol biosynthesis It is a non-competitive inhibitor

Which of the following best describes statins mechanism of action? Group of answer choices It is an irreversible inhibitor It binds to the allosteric site of HMG-CoA reductase It directs the rate-limiting step in cholesterol biosynthesis It is a non-competitive inhibitor

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter27: Metabolic Integration And Organ Specialization

Section: Chapter Questions

Problem 17P

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Concept explainers

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.

Question

Which of the following best describes statins mechanism of action?

Group of answer choices

It is an irreversible inhibitor

It binds to the allosteric site of HMG-CoA reductase

It directs the rate-limiting step in cholesterol biosynthesis

It is a non-competitive inhibitor

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