Name the six fundamental properties of malignant tumours. Which of these properties are amenable to study in a cell culture model of cancer and why?
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Name the six fundamental properties of malignant tumours. Which of these properties are amenable to study in a cell culture model of cancer and why?
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- The most common therapeutic approaches to treating cancer include all of the following except ________. a. chemotherapy b. irradiation of tumors c. surgery to remove cancerous tissue d. administering doses of vitaminsWhat are the underlying biological mechanisms that differentiate the various types of cancer, and how can a better understanding of these mechanisms lead to more targeted and effective treatments for each specific type of cancer?One of the major characteristics of cancer is uncontrolled proliferation of cells. There are several more characteristics of cancer, name TWO more:
- Excessive angiogenesis and reduced apoptosis are two of the six characteristics that define cancerous tumors. Discuss how developing treatments for these two conditions might prevent the development of cancer altogether from pre-malignant tumors.What types of observations allow a pathologist to identify the tissue of origin of a tumor? Why are certain tumors difficult to assign a specific tissue of origin? What is the importance of assigning a specific tissue of origin?name any two methods that can possibly cure cancer .
- What is inflammation? Describe the main characteristics of inflammation. What characterizes chronic inflammatory disorders? What is the role of NFkB in inflammation and cancer? What are the mechanisms and strategies to inhibit excessive and chronic inflammation? answer should be one page longWhat is the difference between benign and malignant tumors? What is the disadvantage of this classification?Out of these 8 hallmarks ( sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, activating invasion and metastasis, deregulating cellular energetics and metabolism, and avoiding immune destruction). Rank them from least important to most for cancer development. Explain in 2-3 sentences how.
- 1)Briefly describe three chemical factors affecting cell division. 2)Briefly describe the three classifications of cancer based on origin.The best strategy for treating a specific type of human tumor can depend on identifying the type of cell that became cancerous to give rise to the tumor. For some tumors that have colonized a distant location (metastasized), identifying the parental cell type can be difficult. Because the type of IF protein expressed is cell-type-specific, using monoclonal antibodies that react with only one type of IF protein can help in this identification. What IF proteins would you produce monoclonal antibodies against to identify (a) a sarcoma of muscle cell origin, (b) an epithelial cell carcinoma, and (c) an astrocytoma (glial cell tumor)?Explain Three mechanisms for viral induction of cancer.