Draw the structure of the major organic product for the reaction of the carbonyl and amine drawn below under mildly acidic conditions. O ΝΗ, +
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- Show how acid derivatives hydrolyze to carboxylic acids under either acidic or basicconditions. Explain why some acid derivatives (amides, for example) require muchstronger conditions for hydrolysis than other derivatives.1- Arrange the following compounds in order of decreasing reactivity towards hydrolysis. 2- Arrange the following chemical species in order of decreasing basicity.provide a possible synthesis for the following reaction
- Identify the electrophile and the nucleophile in each of the following reaction steps and then draw curved arrows to illustrate the bond-making and bondbreaking processes.Carbonyl compounds can be protonated on the carbonyl oxygen. Protonation of the carbonyl oxygen gives a species whose positive charge is delocalized by resonance. Explain why acetic acid (ethanoic acid) is more readily protonated than acetone (propanone).Rank the following carboxylic acid derivatives in decreasing order (most to least) of reactivity towards nucleophilic acyl substitution.
- ← Problem 17 of 27 Submit Draw the monoalkylation product of an amine reacting with methyl iodide. Ignore any inorganic byproducts. CHзI (1 equiv) NH2 QDraw the major organic product of the Bronsted acid-base reaction between the compounds shown below. Include all lone pairs and charges as appropriate. Ignore any counterions. H H :O: :O: H 1 eq. base :O: H HPrimary amines can also be prepared by the reaction of an alkyl halide with azide ion, followed by catalytic hydrogenation. What advantage do this method and the Gabriel synthesis have over the synthesis of a primary amine using an alkyl halide and ammonia?