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Purdue University *

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Biology

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Oct 30, 2023

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docx

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6.3.U1: Pathogen: A pathogen is a microorganism or agent that can cause disease in the host organism. Skin and mucous membranes form the first line of defense against pathogens. Skin acts as a physical barrier, sebaceous glands produce protective oils, and mucous membranes produce mucus that traps and expels pathogens. 6.3.U2: Benefits of blood clotting when skin is cut: It prevents excessive bleeding, which helps maintain blood volume and pressure. It seals the wound, reducing the risk of pathogens entering the body. 6.3.U3: Two roles of platelets in the blood clotting cascade: They release clotting factors that initiate and promote the clotting process. They adhere to damaged blood vessel walls, forming a plug to stop bleeding. 6.3.U4: Blood clotting cascade: Platelets release clotting factors. Clotting factors activate one another in a series of reactions. Thrombin is formed, which converts fibrinogen into fibrin. Fibrin forms a mesh that traps blood cells to create a clot. 6.3.U5: White blood cells are the second line of defense against pathogens. Phagocytic white blood cells ingest and destroy pathogens by engulfing them in a process called phagocytosis. 6.3.U6: Specific immune response: The immune system's targeted defense against a particular pathogen. Antigen: A foreign substance that triggers an immune response. Antibody: Y-shaped proteins produced by lymphocytes that bind to antigens and neutralize or mark them for destruction. Structure: Antibodies have variable regions that recognize antigens and constant regions that activate immune responses. Plasma cells produce antibodies, while memory cells "remember" the pathogen for future responses. 6.3.U7: Antibiotic: A substance that inhibits or kills bacteria by targeting processes specific to prokaryotic cells. Antibiotics kill bacteria by disrupting cell wall synthesis, protein synthesis, DNA replication, or other bacterial processes.
Antibiotics are ineffective against viruses because viruses lack the cellular machinery targeted by antibiotics. 6.3.U8: Antibiotics are ineffective against viruses because viruses do not possess the cellular processes targeted by antibiotics, as they lack metabolism. 6.3.U9: Measures to avoid antibiotic resistance: Completing the full antibiotic course. Avoiding unnecessary antibiotic use. Proper hygiene and sanitation practices. Developing new antibiotics. Implementing strict antibiotic prescription guidelines. Multiple drug antibiotic resistance is dangerous because it limits treatment options for bacterial infections. Example of multidrug-resistant bacteria: Methicillin-resistant Staphylococcus aureus (MRSA). 6.3.A1: Coronary arteries supply the heart with oxygen and nutrients. Coronary thrombosis: Formation of blood clots in coronary arteries. Sources of arterial damage increasing thrombosis risk include atherosclerosis, smoking, hypertension, and diabetes. 6.3.A2: HIV compromises the immune system by attacking CD4+ T cells. HIV is the virus that leads to AIDS (Acquired Immunodeficiency Syndrome). HIV spreads through unprotected sexual contact, sharing needles, blood transfusions, and from mother to child during childbirth or breastfeeding. 6.3.A3: Florey and Chain's experiments tested penicillin on bacterial infections in mice. They injected mice with lethal bacterial infections and treated some with penicillin. Results showed that penicillin effectively treated bacterial infections, saving the lives of the treated mice. 11.1.U1: Antigen: Unique molecules on the surface of cells that can trigger an immune response. Example antigen molecules include proteins, carbohydrates, and viral components. 11.1.U2:
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