Suggest different strategies on the following aspects of COVID-19: a. Diagnostics b. Vaccines
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- Briefly explain what type of disease COVID-19 is and how it is transmitted. Select one of the approved and recommended vaccines listed on the CDC site and explain its mechanism of action, and be sure to include: Is the vaccine an mRNA or viral vector vaccine? Explain how it works within the body. How many doses are administrated? If multiple doses (or boosters) are needed, explain the importance. What are two ingredients found in the vaccine and some of the most common side effects? How do vaccines assist our immune system against emerging diseases?(c) Molnupiravir has not been approved but has been authorized for emergency use by the FDA under an EUA to treat mild to moderate COVID-19 infection. Briefly explain this decision made by FDA based on the knowledge of clinical trials. (d) Both drugs are not allowed to be prescribed to person under 18 years old due to insufficient clinical data. Why is it necessary to separately conduct clinical trials for a younger age group?Describe Covid-19, it’s mechanism of entry, and it’s deleterious effects. Be specific about receptor type used for viral entry.
- Briefly describe the mechanism by which Covid-19 affects the body system of concern.What are those methods being used in clinical practice of covid-19?Which of the following statement is false regarding the SARS-CoV-2 protease Mpro? a) Mpro catalyze the translation of viral RNA into polyproteins b) Mpro is an ideal drug target because its structure is largely conserved across the SARS-CoV family c) N3 is an irreversible inhibitor that block the substrate binding site of Mpro d) Mpro forms a dimeric structure and each protomer is composed of three domains
- In 1994, the U.S. Public Health Service identified “10 Essential Public Health Services.” For each of the ten, briefly describe a specific activity that has been used in the response to COVID-19.Cite technological advancement that helps fight COVID-19.c) pien Nutriceutical Give examples of medications prescribed in alternative medicine. Is it necessary to take precautions in the use of Such medicines? Explain. What natural products are being explored as prospective protection or treatment against Covid-19? Elaborate on each very briefly why they are considered as such. Corabree
- During HAART therapy for Human Immunodeficiency Virus (HIV), what are the rationale and mechanisms of action for NRTIs, NNRTIs, and protease inhibitors?Consider the factors that lead to emergency of new infectious disease, which ones do you think could have contributed to COVID-19 and why?Make a list of five preventive measures you and your family continuously practice to stop the spread of COVID-19.