Q4. Prednisolone is to be eluted from a silica gel column. List the following system in order of decreasing rate at which they will elute prednisolone (i) Hexane/isopropanol (90:10), (ii) dichloromethane/ methanol(90:10), (iii) dichloromethane/methanol(80:20) HO. Prednisolone

Organic Chemistry
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ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
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Chapter23: Amines
Section23.6: Reactions With Acids
Problem 23.9P
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4.. Q4. Prednisolone is to be luted from a silica gel column. List the following system in order of decreasing rate at which they will elute prednisolone
Q4. Prednisolone is to be eluted from a silica gel column. List the following system in order of
decreasing rate at which they will elute prednisolone
(i)
Hexane/isopropanol (90:10), (ii) dichloromethane/ methanol(90:10), (iii)
dichloromethane/methanol(80:20)
OH
Но
OH
H
H
Prednisolone
Transcribed Image Text:Q4. Prednisolone is to be eluted from a silica gel column. List the following system in order of decreasing rate at which they will elute prednisolone (i) Hexane/isopropanol (90:10), (ii) dichloromethane/ methanol(90:10), (iii) dichloromethane/methanol(80:20) OH Но OH H H Prednisolone
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