Kindly refer to the image and answer the question5. Cite a metabolic pathway where active protein kinase is needed and explain its mechanism of action 1 Unoccupied receptor doesnot interact with G, protein.Extra-collularspace-Hormone or neuro-transmitterCellmembraneGs proteinwith bound GDPSynaptic signalingReceptorTargetcellInactive adenylylCytosolGOPcyclaseNervecellOccupied receptor changes2 shape and interacts with asubunit of G, protein. G, proteinreleases GDP and binds GTP.NeurotransmitterEndocrine signalingHormoneInactiveadenylylcyclaseGTPTargetcellGDPa Subunit of G, protein3 dissociates from By andBlood vesselactivates adenylyl cyclase.ActiveadenylylcyclaseDirect contactАТРGapjunctionGTPCAMP + PPWhen hormone is no longer4 present, the receptor revertsto resting state. GTP on thea subunít is hydrolyzed to GDP,a rejoins By, and adenylylcyclase is deactivated.SignalingcellTargetcellsInactiveadenylylcyclase

Protein kinases are the Enzymes that phosphorylate the Target protein by adding a phosphate group.…

Answered: Kindly refer to the image and answer…

Kindly refer to the image and answer the question 5. Cite a metabolic pathway where active protein kinase is needed and explain its mechanism of action

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter9: Cell Communication

Section: Chapter Questions

Problem 12RQ: Histamine binds to the H1 G-protein-linked receptor to initiate the itchiness and airway...

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Question

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Kindly refer to the image and answer the question

5. Cite a metabolic pathway where active protein kinase is needed
and explain its mechanism of action

1 Unoccupied receptor does
not interact with G, protein.
Extra-
collular
space
-Hormone or neuro-
transmitter
Cell
membrane
Gs protein
with bound GDP
Synaptic signaling
Receptor
Target
cell
Inactive adenylyl
Cytosol
GOP
cyclase
Nerve
cell
Occupied receptor changes
2 shape and interacts with a
subunit of G, protein. G, protein
releases GDP and binds GTP.
Neurotransmitter
Endocrine signaling
Hormone
Inactive
adenylyl
cyclase
GTP
Target
cell
GDP
a Subunit of G, protein
3 dissociates from By and
Blood vessel
activates adenylyl cyclase.
Active
adenylyl
cyclase
Direct contact
АТР
Gap
junction
GTP
CAMP + PP
When hormone is no longer
4 present, the receptor reverts
to resting state. GTP on the
a subunít is hydrolyzed to GDP,
a rejoins By, and adenylyl
cyclase is deactivated.
Signaling
cell
Target
cells
Inactive
adenylyl
cyclase

Chemical pathways by which living things function, especially those that provide cellular energy, such as the transformation of energy from food into the energy of ATP. Metabolism also focuses on chemical pathways involving the synthesis of new biomolecules and the elimination of waste.

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