A urethane is a molecule in which a carbonyl group is part of an ester and an amide (it is an amide in one direction and an ester in the other direction). Propose a mecha- nism for the reaction of an isocyanate with an alcohol to form a urethane. -N=C=0+ ELOH -NH-C-OEt Phenylisocyanate Ethanol A urethane

Organic Chemistry
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Author:John E. McMurry
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Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions
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Problem 75AP: One frequently used method for preparing methyl esters is by reaction of carboxylic acids with...
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A urethane is a molecule in which a carbonyl group is part of an ester and an amide
(it is an amide in one direction and an ester in the other direction). Propose a mecha-
nism for the reaction of an isocyanate with an alcohol to form a urethane.
-N=C=0+ ELOH
-NH-C-OEt
Phenylisocyanate
Ethanol
A urethane
Transcribed Image Text:A urethane is a molecule in which a carbonyl group is part of an ester and an amide (it is an amide in one direction and an ester in the other direction). Propose a mecha- nism for the reaction of an isocyanate with an alcohol to form a urethane. -N=C=0+ ELOH -NH-C-OEt Phenylisocyanate Ethanol A urethane
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