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Essay On Dynamic Membranes

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3. Inclusion/Exclusion criteria: Cells’ data bank will be screened to determine the dynamic membrane properties for each cell group and to ensure they meting all inclusion and exclusion criteria. Cells will be excluded from the study if they fall under one of the following: (1) Unhealthy neural cells (2) neural cells that have different diameter or geometric shape (3) cells that don’t contain all the required parameters values, (4) Cancer cells (5) Uncomplete data set. 4. Sample size calculation: To determine the sample size needed for all groups, an a priori power analysis, conducted using G*Power 3.0.10 software, calculated the required sample size n = 30 per group bases on an ANOVA test that has 80% power to detect a significant …show more content…

Alternatively, it is possible that the statistical test find significant difference between trials, which is an indication of the in consistency of the algorithm. In this case we would revise out algorithm and experimental design, we also may increase the number of trials to re-examine the consistency of the algorithm. Also the statistical test may reveal no significant difference between groups, in this case we will re construct the groups based on manipulation of three parameters, and we will revisit the range of variation for each parameter. 2. Exp2: We predict a significant difference between groups, waveforms and the interaction between both of them, and the post hoc test will reveal that groups with variation in Gnamax, Gleak and α will be more selective than groups with them constant. This is an indication that Gnamax, Gleak and α can be used to improve stimulation selectivity. However, the test may show no significance between groups, in this case we will revise the parameters combinations. Also, We may run the statistical test relatively to the stimulus strength (K) instead of NOC. In this case we should revise the parameters variation range and confirm that all cells is stable when running the test. 3. EXp3: Results from experiment 2 will guide us

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